Tetracyclines, Dry skin, Calcium/Magnesium/Trace minerals
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TheMediumDog Forum Moderator

Joined: 17 Aug 2007 Location: UK
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| Posted: Fri Feb 08, 2008 9:34 am Post subject: |
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| Quote: | | I think the buffer is mitochondrial function. Almost all the conditions you describe, and many more within the rosacea spectrum, can be associated with mitochondrial dysfunction. |
Could you expand a little, on the how's and why's? |
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kristina b
Joined: 30 Jan 2008
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| Posted: Fri Feb 08, 2008 10:08 am Post subject: |
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Yes, this is all very interesting. Don't think I'm going to take any new supplements or anything at moment - just been diagnosed and trying to "observe" what's going on. But I too flush at certain times in the day, regardless of what I do/eat/the temperature. Not sure about raynauds, but my husband's always telling me there's something wrong with my hands as they're constantly freezing(!) and they go blotchy after being out in the cold. The thyroid and body temperature bit has always confused me - having an underactive thyroid, as I do, is of course meant to make you feel the cold more; but I was never like that, I was always the one who felt boiling and insisted on opening the windows!
I'd love to understand all these connections. Sadly I don't think GPs have the time/inclination to pursue any of this. It's usually a case of treating everything separately.
Kristina |
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TheMediumDog Forum Moderator

Joined: 17 Aug 2007 Location: UK
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| Posted: Fri Feb 08, 2008 12:19 pm Post subject: |
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| Quote: | | Don't think I'm going to take any new supplements or anything at moment - just been diagnosed and trying to "observe" what's going on. |
Sensible.
| Quote: | | Not sure about raynauds, but my husband's always telling me there's something wrong with my hands as they're constantly freezing(!) |
Mine too, and that's what I'm calling mild Raynaud's. In proper Raynaud's its a lot more serious; but still, I think the cause must be the same. |
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caran
Joined: 28 Oct 2007
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| Posted: Fri Feb 08, 2008 1:59 pm Post subject: |
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Mitochodrial dysfunction is associated with cpn infection. The bacteria act as parasites using up the cells' atp as it can't produce it's own. Cpn may be associated with many autoimmune conditions including thyroid disease.
Of course this won't be the cause for all rosacea sufferers but it may be a factor for many. |
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Lookout
Joined: 28 Aug 2006
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| Posted: Fri Feb 08, 2008 2:15 pm Post subject: |
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Very interesting about the Ichthyosis/HDD and cal....no I don't have anything that similiar to this disease but rather found it had something to offer in that the need to constantly remove the top dead layer of skin....sounded fimiliar but what I deal with is not on a level like them.
I am going to have my blood levels checked for cal/mag and vit d....this is the only way to know what is low if anything for sure.
I too have low thyroid/hashimoto's disease....I only recently got my levels back to a normal range....in my case my antibodies were in the thousands attacking my thyroid gland even though my other levels (TSH & free T3) appeared normal....I had awful symptoms....fatigue (couldn't get enough sleep), muscle aches (like I had flu) and so on...of course dry skin....this hasn't changed even with thyroid replacement treatment. I should clarify all my symptoms resolved except the dry skin.  _________________ Dx 1998
No meds
Used low-dose accutane successfully |
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melissawohl Forum Moderator

Joined: 08 Jan 2007 Location: new york
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| Posted: Fri Feb 08, 2008 2:57 pm Post subject: |
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| caran wrote: | Mitochodrial dysfunction is associated with cpn infection. The bacteria act as parasites using up the cells' atp as it can't produce it's own. Cpn may be associated with many autoimmune conditions including thyroid disease.
Of course this won't be the cause for all rosacea sufferers but it may be a factor for many. |
I think this is a very important point. In conditions such as SIBO, IBS, hypothyroidism, Rheumatoid Arthritis, Chronic Fatigue Syndrome, Rosacea, etc. there may be an infection with Chlamydia Pneumoniae. I wish our doctors were more open to this possibility as testing can be negative depending on what phase you get the cpn in.
Melissa |
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Steve95301

Joined: 23 Jul 2005
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| Posted: Fri Feb 08, 2008 4:57 pm Post subject: |
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| TheMediumDog wrote: | | Quote: | | I think the buffer is mitochondrial function. Almost all the conditions you describe, and many more within the rosacea spectrum, can be associated with mitochondrial dysfunction. |
Could you expand a little, on the how's and why's? |
There's a thread here about LLLT increasing mitochondrial respiration and I've also put down a few thoughts over here.
I'm currently researching this subject for a term paper I'm writing, and I'll post the whole thing here when I'm done. It's about the role of ROS and the mitochondria in rosacea.
I think rosaceans cannot utilize oxygen efficiently, and our vessels dilate in compensation. In some cases, Cpn may be impairing the mitochondria. _________________ KNOWLEDGE = POWER |
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TheMediumDog Forum Moderator

Joined: 17 Aug 2007 Location: UK
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| Posted: Thu Feb 14, 2008 11:00 am Post subject: |
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| Quote: | | Can people take hyaluoronic acid as a supplement |
I may have been wrong to dismiss this - or, the source I pasted up may have been wrong. In this interesting interview, a researcher explains that the rationale for people doubting whether oral HA would work was that the molecular weight was too high, so the digestive system wouldn't process it (I don't know the biology, maybe someone does?).
But apparently, the molecular weight of the HA in oral supplements is far lower. And in any case, the original objection may have been invalid anyway:
| Quote: | The oral HA products are mostly of low molecular weight. HA in an injectable form ranges from 3 million to 6 million daltons molecular weight, while some oral forms are as low as about 1,500 to 3,000 daltons. A dalton is a unit of mass equal to the mass of a single hydrogen atom...
Passwater [interviewer - M.D]: I have seen test results of one oral HA supplement that determined it was about 5,000 daltons. It seems logical that the smaller molecular weight forms of HA are more easily absorbed in the intestines, but that may not be the complete story. Clinical results are what are important.
Sardi [interviewee - M.D]: ... Some doctors question whether oral HA is absorbed, mistakenly believing it is the same high molecular weight molecule as injectable HA. |
Anyway, I'm still looking into it, but I may well try an HA supplement for my dry skin. I think it really needs to be combined with an antioxidant that stops the degradation of HA - otherwise you'd be generating stuff that got scrapped. That is, if the initial problem was not so much with the production of HA as its degradation, which I believe may be so in my case.
On the other hand, I am rather suspicious, since there's clearly some cunning marketing strategies being pursued at the moment to get HA out there and hyped. Lots of 'independent' websites which happen to have links to stockists, and so on. Who knows if this Dr. Sardi has a commercial interest in HA. I hate capitalism, it ****s everything up. |
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TheMediumDog Forum Moderator

Joined: 17 Aug 2007 Location: UK
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| Posted: Thu Feb 14, 2008 1:33 pm Post subject: |
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| Quote: | | I think rosaceans cannot utilize oxygen efficiently, and our vessels dilate in compensation. In some cases, Cpn may be impairing the mitochondria. |
Interesting reading. A high 'density' of connections between some putative cause and other diseases and symptoms regularly experienced by rosaceans always seems to me to indicate the right track; and this looks encouraging. |
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